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Human SLC46A2 Is the dominant cGAMP importer in extracellular cGAMP-sensing macrophages and monocytes

Nucleophilic attack Attack of an electron-rich species (the nucleophile) on an electron-deficient species (the electrophile), forming a new bond between the nucleophile and the electrophile

Benzyl isothiocyanate inhibits prostate cancer development in the transgenic adenocarcinoma mouse prostate (TRAMP) model, which is associated with the induction of cell cycle G1 arrest

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Chemicals and reagents RSL3 (Selleck, 0.52 M), ferrostatin-1 (Fer-1, Selleck, 25 M), and deferoxamine (DFO, Selleck, 100 M) were dissolved in DMSO and used at indicated concentrations