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Animal studies have shown that GLUT-1 deficiency in brain ECs, rather than in astrocytes, due to BBB breakdown, which exacerbates AD, thereby accelerating A accumulation and cognitive impairment (Winkler et al., 2015)

Autophagy plays multifaceted roles throughout disease progression, particularly in tumor

These patients reported by Cameron et al

mTOR signaling to translation

Interestingly, these changes to proteoglycan gene expression were not accompanied by any changes to matrix metallopeptidase 3 (MMP-3) gene expression in either age group (Figure 4E)

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