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TA significantly reduces the recurrence rate of melasma upon discontinuation of the medicine

[DOI] [PMC free article] [PubMed] [Google Scholar] 5.Plawecki MH, Crabb DW

For overweight or insulin-resistant patients, a lower starting dose (0.10.15 mg) may reduce transient water retention

There was considerable variation in risk of suicidality among drugs, but a tendency toward an increase in the younger patients for almost all drugs studied