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however, a recent Cochrane systematic review showed that no randomized controlled trials have been conducted that evaluate the role of exercise in cancer cachexia.[47] While exercise has therapeutic potential in the treatment of cancer cachexia, concerns about compliance with an exercise regimen can be problematic and limit the potential benefits of exercise in frail and chronically fatigued cancer patients

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In the pathological progression of DN, iron deposition leads to ferroptosis and destroys kidney cells

It necessitates the screening and identification of trustworthy and accurate PD markers to fulfill the goal of early diagnosis of PD

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