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Trends in Biotechnology, 39(9), 972987

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The solid oral pharmaceutical composition according to any one of items 1 to 17, 22 and 23, wherein the copolymer (C) in the first coating comprises not more than 3 mol-% methyl acrylate repeating units, preferably wherein the copolymer (C) comprises not more than 1 mol-%, more preferably not more than 0.5 mol-%, even more preferably not more than 0.1 mol-%, yet even more preferably not more than 0.01 mol-%, still more preferably 0 mol-% methyl acrylate repeating units

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Nevertheless, personal or family history of medullary thyroid carcinoma or multiple endocrine neoplasia type 2 (MEN 2) represents an absolute contraindication to tirzepatide use