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Parkinsons disease, characterized by the degeneration of dopaminergic neurons and the aggregation of -synuclein, polyphenols again show promise (409)

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the inhibition of the PTEN axis [217] or the protein deglycase DJ-1 (DJ-1) known to exhibit anti-oxidative and cyto-protective functions in other diseases [218220] might have therapeutic potential, since DJ-1 is often upregulated in cancer cells and involved in the regulation of various redox stress responsive signaling pathways (PI3K/AKT/PKB