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At present, some drugs containing saponins or total saponin extracts are used for clinical cancer patients in the Chinese pharmaceutical market

However, in subsequent investigations in rodent models of depression, (2R,6R)-hydroxynorketamine did not exhibit antidepressant-like effects and increased aggressive behavior (Yang et al., 2019)

Human subject gut microbiota suppression was achieved using a cocktail of oral poorly absorbed antibiotics as previously described (7)

167 The breast cancer cells can engulf exosomes secreted by senescent neutrophils, thereby enhancing their resistance to chemotherapy

A total of 28 metabolites were found to be significant features for further analyses based on a log2 fold change cutoff of 1.5 at 10% false-discovery rate (Figure 1A

PaP: Data curation, Formal Analysis, Investigation, Validation, Writingoriginal draft