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Aging as a key modulator of ferroptosis susceptibility Advanced age is the most significant non-modifiable risk factor for major cognitive disorders, including AD, PD and DACI (98-100)

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In this context, individuals with ASD often exhibit impaired judgment of facial expressions, inaccurately labeling neutral faces as negatively valenced, with reduced eye contact correlating with increased amygdala reactivity and threat ratings (87)

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Additionally, IF staining for macrophage polarization markers revealed synovial microenvironment remodeling