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The biology behind it is not fully settled, but dose-response curves that peak and then fall off are common for signaling molecules, where too much of a stimulus can desensitize or overshoot the system it is meant to nudge

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doi: 10.1016/j.biopha.2022.112879 85 RenYLiSSongZLuoQZhangYWangH

This article describes the design and synthesis of a peptide that replicates the multi-hierarchical self-assembly of natural collagen into native triple helix conformation

1.3.3 DHA and EPA (Omega-3 fatty acids) Docosahexaenoic acid (DHA) and eicosapentaenoic acid (EPA) are essential omega-3 fatty acids involved in neuronal membrane stability, synaptic plasticity, and anti-inflammatory signaling (Zhang E