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This formulation is particularly beneficial for patients who have difficulty swallowing pills, such as children and the elderly, or those with conditions that impair their ability to ingest solid forms of medication

Severe liver disease, severe anemia, severe abnormal blood biochemistries, or renal failure (eGFR 1 g fish oil, and/or drugs that affect insulin sensitivity, and/or thyroid treatment

Combinations often provide a greater benefit than individual agents [443]

Revised: 3/2026 Full Prescribing Information WARNING: LIFE THREATENING ADVERSE REACTIONS Hepatotoxicity General Population: Hepatic failure resulting in fatalities has occurred in patients receiving valproate and its derivatives

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Heart failure or significant cardiac conditions: IV fluid volume can increase cardiac workload