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Metabolomic profiling of human serum samples after ingestion of a pine bark extract (Pycnogenol )

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qRT-PCR analysis revealed the marked upregulation of CDKN2A (encoding p16) , CDKN1A (encoding p21) , interleukin-8 ( IL-8) , and matrix metalloproteinase ( MMP)-12 expression (Figure 1D)

Furin inhibits epithelial cell injury and alleviates experimental colitis by activating the Nrf2-Gpx4 signaling pathway

It is known that GSH is required for cell division in the root apex (Vernoux et al., 2000) and that GSH levels regulate the G1-to-S-phase cell-cycle transition ( In wild-type nodules, the amount of GSH label in bacteria in infection threads was low (Supplementary Figure 3A and Table 2), with the most intensive labeling being observed in bacteria in some locked infection threads of sym33-3 mutants (Figures 3DF) and juvenile bacteroids of sym33-3 and sym40-1 mutants (Figures 2DF, 3JL, 4D)