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Ciccone L et al (2020) The positive side of the Alzheimers disease amyloid cross-interactions: the case of the A 142 peptide with Tau, TTR, CysC, and ApoA1

intracranial, portal, and caval hypertension

Recent work has shown that embryonic sensory neurons deprived of NGF results in PKC activation, ROS production, and TRPV1 activation which in turn induces a large increase in axoplasmic Ca 2+ required for degeneration (Johnstone et al., 2018, 2019)

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Though these approaches are reasonable for relatively homogenous tissues, nerves do not meet key assumptions underlying such models (e.g., Gaussian scatterers randomly distributed in a dilute medium)

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