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Methyltransferase SETD2-mediated methylation of STAT1 is critical for interferon antiviral activity

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Conversely, inhibitors targeting key enzymes or transporting proteins in the glycolytic pathway could reduce the energy supply to tumor cells and inhibit tumor growth

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We conclude that while cytokines do conform to the inflammation model of obesity and T2D, their clinical utility as standalone predictive or diagnostic markers is limited

The foundational mechanism papers from the Washington State University lab were retracted in April 2025 after a misconduct finding of image manipulation