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doi: 10.1038/s41584-025-01223-y 2 GBD 2021 Osteoarthritis Collaborators

Dysbiosis, or microbial imbalance, exacerbates chronic inflammation and disrupts tissue regeneration

In order to come up with clear recommendations, more research is required

Thats why theyre often described as supportive and regenerative, and why they layer well with other routines

If naloxone is prescribed, also advise patients and caregivers: How to treat with naloxone in the event of an opioid overdose To tell family and friends about their naloxone and to keep it in a place where family and friends can access it in an emergency To read the Patient Information (or other educational material) that will come with their naloxone