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Pain Physician 17 (4), E525E530

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Irvine KA, Ferguson AR, Mitchell KD, Beattie SB, Beattie MS, Bresnahan JC

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We have previously developed an individual-centric spheroid system using blood sera to better mimic the human livers response to drugs than standard preclinical models, reproducing interindividual variability (Roux et al., 2024b