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Description

Heres the whole thing in plain terms: What they did: built and validated a lab-grade method to accurately measure 5A1MQ in the blood, then dosed rats two ways intravenous (IV) and oral and tracked exactly how much showed up in circulation over time

It has been observed that the conversion from 2-hydroxysetrogens to 4-hydroxyestrogen might be an additional pro-inflammatory signal because these endogenous metabolites can be oxidized to 3,4-quinone, which lead to depurination and mutation [49]