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These adaptations may explain why metabolic benefits can continue to improve over weeks to months of consistent use, rather than plateauing immediately

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Collagen also exhibits an affinity for water, and it appears to hydrate the skin cells and Extracellular Matrix when it penetrates the skin barrier

Because AOD-9604 does not interfere with growth hormone signaling or insulin pathways, it is considered a safer option for long-term metabolic support under medical supervision

For individuals whose primary challenge is overeating, this represents a significant limitation