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Drug Des Devel Ther 17:181190

[Clinical efficacy of intravenous L-carnitine in patients with right-sided heart failure induced by pulmonary arterial hypertension]

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In some contexts it is suggested that it could support mitochondrial function or neuronal signalling, but the clinical evidence is heterogeneous and does not allow generalisation of benefits to the whole population

Insulin sensitivity pilot study (Ruggenenti): A pilot study in nondiabetic subjects at increased cardiovascular risk with insulin resistance found that 2 g/day of oral ALCAR for 6 months improved insulin-mediated glucose disposal (measured by euglycemic hyperinsulinemic clamp) alongside reductions in blood pressure [5][21]