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Additionally, TB-500 demonstrates cardioprotective effects through preservation of cardiac muscle viability following ischemic injury and promotion of cardiac muscle regeneration

TABLE 1 qRT-PCR Primers

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Tirzepatide vial (lyophilized powder, check the mg amount on the label) Bacteriostatic water (not sterile water, not saline, not tap water) Insulin syringes (U-100, choose 0.5mL or 1.0mL based on your water volume) Alcohol swabs (70% isopropyl alcohol prep pads) Clean, flat surface (disinfected with alcohol wipe) A note on water types for peptide mixing : bacteriostatic water contains 0.9% benzyl alcohol, which prevents bacterial growth and allows the vial to be used over multiple doses across up to 28 days

Loss of p53 expression reinforced HGF/c-Met signaling, which promoted invasion and metastasis by upregulating Snail expression (Liu et al., 2016)

Funding This research was supported by the China Postdoctoral Science Foundation (2021M701420), Guangdong Basic and Applied Basic Research Foundation (2022A1515110021), Guangzhou Science and Technology Projects Foundation (202201020002), Scientific Research Project of Guangdong TCM Bureau (20221105), Guangdong Medical Research Foundation (A2022214)