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Finally, upon sufficient evidence, regulatory acceptance can be sought through endorsement by agencies or inclusion in clinical guidelines, allowing the biomarker to be used in routine practice or as an endpoint in drug development

Australas Med J 6(7):350-3, 2013

Pharmacology of combination chemotherapy of cytosine arabinoside (ara-C) and uracil arabinoside (ara-U) or tetrahydrouridine (THU) against murine leukemia L1210/0 in tumor-bearing mice