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References: Kang, D., Shi, B., Erfe, M.C., Craft, N

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This parenteral preparation is unlikely to pose a threat of fluid overload except possibly in very small infants

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Cardiovascular effects, such as a rise in blood pressure and tachycardia, were usually mild, while the risk of seizure, which was high with the original bupropion formulation, has been significantly reduced with the advent of bupropion-SR and bupropion-ER