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Acrolein contributes to the development of diabetic nephropathy by promoting the accumulation of extracellular matrix, increasing the production of angiotensin II (Ang II), activating MAPK signaling pathways that phosphorylate JNK, ERK, or p38, increasing the expression of inflammatory cytokines such as IL-6, IL-1beta, IL-18, and TNF-alpha, and cleaving caspase 9, caspase 3, and PARP (119)

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This reconsideration process would be conducted once per program fiscal year after validation of HAIs for all four quarters of the given fiscal year's data period and after the confidence interval has been calculated

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Learning from pathophysiological aspects of COVID-19 clinical, laboratory, and high-resolution CT features: a retrospective analysis of 128 cases by disease severity

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The proteome of cblC defect: in vivo elucidation of altered cellular pathways in humans

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(Shan et al., 2021

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