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doi: 10.1016/j.ab.2016.10.021, 151

Constitutively active STING causes neuroinflammation and degeneration of dopaminergic neurons in mice

By improving mitochondrial function and indirectly activating Nrf2, metformin augments antioxidant capacity and contributes to sustained cardiometabolic protection (Mthembu et al., 2025)