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Mediation of metabolism KEAP1 Loss of kelch-like ECH-associated protein 1 (KEAP1) leads to release of Nrf2, allowing its translocation to the nucleus, where it activates antioxidant gene transcription, helping cells counteract oxidative damage [81]

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Cell viability assay NCI-H2009 cells were seeded into 96-well culture plates at a density of 8,000 cells per well

doi: 10.1080/03007995.2018.1538011 57 Merck

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