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Consent for publication This is to confirm that the work has not been and will not be submitted simultaneously to another journal, in whole or in part

Science 333 , 13031307 (2011)

the peptide comprises a peptide comprising or consisting of 8 or more contiguous amino acids from the amino acid sequence of any one of SEQ ID NOs 1-75

Moreover, both hypoxia (via HIF-1) and TGF signaling can independently stimulate the VEGF and CXCR4 expression to drive breast cancer bone metastases (107)