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It may also help regulate appetite and improve insulin sensitivity, making it a valuable tool in reducing the risk of age-related metabolic imbalances such as insulin resistance and type 2 diabetes

*Correspondence: Yelena Budovskaya and Hans van der Spek, Swammerdam Institute for Life Sciences, University of Amsterdam, Science Park 904, Amsterdam 1098 XH, Netherlands

The neuroprotective effect of silymarin has been demonstrated in models of NDs 204 , 205

doi: 10.3389/fnagi.2022.879021 12 BloomG

To improve the appearance of dark spots and pigmentation, make sure to use sunscreen daily, because sun exposure may increase the appearance of pigmentation

That said, lower dose topical OTC products that contain salicylic acid have been reported safe by the American College of Obstetricians and Gynecologists (ACOG)