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Experimental validation Dose response curves and determination of IC 50 values were assessed for the 12 candidate drugs using 3-fold dilution series (see Supplementary Methods (Supplementary File 1) for more details)

The factors that affect the risk for anaphylactic-type reactions to iron dextran products are not fully known but limited clinical data suggest the risk may be increased among patients with a history of drug allergy or multiple drug allergies

BPC-157's effects in rodent vascular injury models are striking, but rodent veins aren't human veins, acute experimental injuries aren't chronic venous disease, and doses that work systemically in a 300-gram rat don't translate linearly to a 70-kilogram human

In: Selenium, Its Molecular Biology and Role in Human Health, (DL Hatfield, MJ Berry, VN Gladyshev (eds.)

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Supplementation of PQQ may reversed the alterations observed in the hippocampus of D-gal-induced mice, including elevated levels of MDA, ROS, as well as reduced T-AOC activity (Zhou et al., 2018)