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The assay is based on the conversion of a luciferin derivative into luciferin in the presence of glutathione, catalyzed by glutathione S-transferase (GST)

Furthermore, inducing ferroptosis by inhibiting the cellular antioxidant system presents a potential therapeutic strategy for OS, as various anticancer agents exert their effects by targeting antioxidant system-related proteins such as GPX4 ( 3 Ferroptosis in bone microenvironment The bone microenvironment encompasses the local setting where bone tissue resides, comprising key cellular components such as osteoblasts, osteoclasts, and osteocytes within the tissue, along with adipocytes, vascular networks, immune cells, and an abundance of bone marrow and extracellular matrix (81)

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Chemopreventive role of anthocyanins in atherosclerosis via activation of Nrf2ARE as an indicator and modulator of redox

FTH1, SLC7A11, GPX4 and STAT3 are upregulated in 5-FU-resistant cells