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These benefits have been observed in women at various life stages, including premenopausal, perimenopausal and postmenopausal groups[3]

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This principle has led to the widespread practice of supplementing poultry diets with fat in hot climates, where the addition of fat helps increase dietary energy levels and reduce the detrimental impact of HS on bird performance

doi: 10.1093/eurheartj/ehv043

however, both the AMEERA-3 phase 2 and AMEERA-5 phase 3 trials did not meet their efficacy endpoints for Amcenestrant as monotherapy or when combined with CDK4/6 inhibitors