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Healthcare services administering B12 injections should have anaphylaxis protocols and equipment available

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As B12 is a water-soluble vitamin, it's generally considered safe (because any not used will be excreted via your urine), but even so you shouldn't take more than the recommended doses unless recommended to do so by your GP, as some studies have shown possible negative impacts of overdoing it

A deficiency in vitamin B12 can lead to fatigue, weakness, and even permanent nerve damage