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Problems of pathogenesis and Pathogenetic therapy of COVID-19 from the perspective of the general theory of pathological systems (general pathological processes)

In cancer cell lines, the mTORC1 signal can also promote de novo lipid synthesis through the sterol responsive element-binding protein (SREBP) transcription factors, which induce the expression of metabolic genes responsible for lipid biosynthesis, including fatty acid synthase (FASN) (Duvel et al., 2010)

Successful treatment of noise-induced cochlear ischemia, hypoxia and hearing loss

Research involving preclinical models (e.g., mice, rats) where NMN was administered

Withdrawal responses were measured using a von Frey filament around the wound before surgery and for the next seven days