They try not to stay too long with the mouse they have already examined and evaluated, spending most of their time getting to know the second mouse, which is newer
activates decorin expression for proper collagen organization
Results: In the first 12 months, 902 patients were enrolled, and 880 were analysed (median age: 74 years
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Abbreviations 5Bs: Bioavailability, Biopersistence, Bioprocessing, Biomodification, and Bioclearance (of nanoparticles) ABB: Air-Blood-Barrier AM: Alveolar Macrophages AuNP: Gold NanoParticle BAL: BronchoAlveolar Lavage BALT: Bronchus-Associated Lymphoid Tissue BaP: Benzo-a-Pyrene BMD: BenchMark Dose BSA: Bovine Serum Albumin CNS: Central Nervous System CPC: Condensation Particle Counter EC: Elemental Carbon EC1: Epithelial type 1 Cells EC2: Epithelial type 2 Cells EELS: Electron energy-loss spectroscopy EPR: Enhanced permeability and retention GIT: Gastro-intestinal-tract HEC: Human Equivalent Concentration HRTEM: High Resolution Transmission Electron Microscopy ID: Initial Dose IM: Interstitial Macrophages IrNP: Iridium NanoParticle IT: IntraTracheal LOAEL: Lowest Observed Adverse Effect Levels LT-MC: Long-Term Macrophage-mediated Clearance MCC: MucoCiliary Clearance MCNs: MiCellar Nanocomplexes MPPD: Multiple Path Particle Dosimetry N-N: Normal to Normal heart beat rate NOAEC: No Observed Adverse Effect Concentration NOAELs: No Observed Adverse Effect Levels NOM: Natural Organic Matter NP(s): NanoParticle(s) OPC: Optical Particle Counter PEGylation: Modification of (often medical) particle surfaces with PolyEthylene Glycol PM: Particulate Matter PM10: PM smaller than 10 m PM2.5: PM smaller than 2.5 m PSL: PolyStyrene Latex RR50: the frequency of beat to beat heart intervals fluctuating by more than 50 msec SEM: Scanning Electron Microscopy SP-A: Surfactant Protein A SP-D: Surfactant Protein D sp-ICP-MS: single particle Induction Coupled Mass Spectrometry STEM: Scanning Transmission Electron Microscopy TEM: Transmission Electron Microscopy TiO2-NP: Titanium dioxide NanoParticle UFP: UltraFine Particles UICC: Union for International Cancer Control References GBD 2015 Risk Factors Collaborators
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