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Protective effects of ginsenoside Rg1 against carbon tetrachloride-induced liver injury in mice through suppression of inflammation

J Neurochem 116:508521 Pullens B, van Benthem PP (2011) Intratympanic gentamicin for menieres disease or syndrome

As mentioned earlier, under physiological conditions, the body maintains a low serum-free Cu concentration through various proteins such as ATP7A/ATP7B, SLC31A1/CTR1, and Cu chaperone antioxidant protein 1 (ATOX1), thereby reducing the Fenton reaction, oxidative stress, and non-target tissue accumulation mediated by it ( 2+ overload, cancer cells activate the Wnt/-catenin signaling pathway, promote the binding of the -catenin/TCF4 complex to ATP7B, leading to upregulated ATP7B expression, increased Cu efflux, and decreased cytoplasmic Cu concentration, thereby enabling tumor cells to escape the cuproptosis process (Liu et al., 2024)

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