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Upon zinc depletion, SOD1 mutants underwent conformational changes due to zinc dissociation, which resulted in oxidative stress and endoplasmic reticulum (ER) stress 25

286 The toxicity of MSNs to normal cells can be attributed to two aspects: (1) Elevates intracellular oxidative stress by inducing the production of toxic ROS and decreases the expression level of glutathione, which has a role in regulating redox homeostasis, leading to lipid peroxidation and subsequent cell death

Vitamin B12 plays a role in various bodily functions, and some individuals choose injectable supplementation when they have difficulty absorbing B12 through diet alone or prefer a more direct method of delivery

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To avoid this interaction, take vitamin B12 supplements before taking Take vitamin C at least 2 hours later