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Heirali et al., 2019)

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In addition, this deletion completely cancels the increase in ROS production caused by the gmhA deletion , while all other mutations in the genes that regulate the metabolism of cysteine and glutathione, as well as a violation of cystine transport, lead to an even greater increase in the level of ROS in cells with a gmhA deletion

A 1-year randomized controlled trial of deferasirox vs deferoxamine for myocardial iron removal in beta-thalassemia major (CORDELIA)