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Acknowledgements: This research was supported by a grant from Ministry of Science, Education and Sports, Republic of Croatia and there is no existing personal conflicts of interest with any of the authors

In the absence of gallbladder alterations, histological analysis of regenerating livers did not reveal abnormalities or signs of accelerated inflammatory reaction in Gstp1/2 / mice (Figure 2)

The liver increases glutathione production to combat the effects of a high-fat diet

This process can be initiated by iron-catalyzed Fenton chemistry, in which hydroxyl radicals (OH) generated from H 2 O 2 trigger a self-propagating lipid peroxidation chain reaction

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