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Protecting the Endothelium The endothelium is the thin layer of cells lining every blood vessel in your body

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As expected, the groups that took a higher dose of Vit-D (D5 and D5N) exhibited more than a 3-fold increase in 25(OH)D compared to the groups that took the lower dose of vitamin D (D1 and D1N)

These interconnected benefits become particularly pronounced after 6-12 months of consistent use, when the cumulative effects of enhanced cellular energy availability have had time to influence multiple aspects of health and daily functioning

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10 Discussion Cancer is the leading cause of death and immunotherapy has attracted a wide range of attention due to its advantages such as durable response, long-term survival benefit, and lower toxicity and side effects (242, 243), in which immune cells are the target cells for immunotherapy, which as part of the TME are mainly composed of TAMs, DCs, NK cells, TANs, MDSCs and T cells