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In addition to these bacteria, the gut symbiont Akkermansia muciniphila (A

Adjuvant-induced arthritis (AIA) and collagen-induced arthritis (CIA) are the most commonly used animal models for the study of RA, and they are able to mimic the key features of RA, such as the abnormal proliferation of synovial tissues, swelling of the joints, and the destruction of cartilage and bone tissues (108)