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Studies using animal models such as experimental autoimmune encephalomyelitis (EAE) in mice and marmosets, as well as analyses of human cerebrospinal fluid (CSF) and peripheral blood samples, have provided insights into these interactions (136, 137)

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rheumatism, etc (Ryuk et al., 2014)

Additionally, as might be expected, dopamine, glutamate and GABA do not act independently

Gupta 2014

The trial also showed that the combination produced dose-dependent, sustained weight loss without concerning additional adverse effects the side effect profile was broadly consistent with what would be expected from each individual agent