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It is now well established that most peptide hormones and growth factors are initially synthesised as prohormones that are converted to active forms by endoproteolysis at specific sites 34

Since these compounds are water-soluble, the body may safely process them without risk of accumulation [11]

The effects of medically induced weight loss on skeletal muscle

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Furthermore, it can be speculated whether atrophy of the hypothalamus in ALS patients is related to the different IFG-I levels 31

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