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Immunity 46:3850

Beltramo E, Berrone E, Tarallo S, Porta M

Physiological and immunological status of adult honeybees (Apis mellifera) fed sugar syrup supplemented with pentadecapeptide BPC 157

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Probing position N108, we found that incorporation of any other amino acid resulted in a substantially reduced formation of cyanidin ( 8 ) suggesting that the hydrogen-bond interaction of the asparagine to the flavonoid substrate is critical for dehydratase activity, while GSH-transferase activity was comparatively less affected for N108 variants comprising an alanine, histidine, tyrosine or tryptophan (Fig