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Addressing the inherent heterogeneity among HPH patients, arising from diverse etiologies, varying disease severities, and distinct comorbidities, requires future research to actively pursue patient stratification strategies leveraging biomarkers of inflammation, oxidative stress, vasoactive factors, and advanced imaging phenotypes to identify specific subgroups most likely to derive benefit from particular TCM therapies

Quick Reference: Standard Protocol Community-documented protocol: 1 mg subcutaneous in the morning, 5 days on / 2 days off, for 2-week courses repeated 2-3 times per year, with 3-6 months rest between courses

10.1016/j.bone.2016.09.023 148 YagodaN.von RechenbergM.ZaganjorE.BauerA

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Moxibustion can downregulate p53 and ROS, upregulate SLC7A11, GPX4 expression, and reduce ferroptosis