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In general, the probe should be absorbed exclusively via the paracellular pathway, be metabolically inert and freely filtered at the glomerulus without tubular reabsorption (32)

Front Cardiovasc Med 8:768214

E.HooperM

doi: 10.1080/09513590.2024.2381498 191

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The PPP is an important metabolic pathway that produces ribose and nicotinamide adenine dinucleotide phosphate (NADPH), which are essential for several physiologic and biochemical processes, such as the synthesis of fatty acids and nucleic acids