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Therefore, the concentrations of acetic, propionic, and butyric acids in human feces may vary depending on whether IBD is in an active or remission state [89]

PPAR- remt de activiteit van microglia en glia, de belangrijkste immuuncellen die betrokken zijn bij oogontsteking.(91) Opregulatie van PPAR- door curcumine is in preklinisch onderzoek tevens geassocieerd met remming van hypertensiegeassocieerde hartfibrose, remming van colorectale carcinogenese, bescherming van zenuwcellen bij cerebrale ischemiegenduceerde ontsteking, remming van nierfibrose, remming van diabetes gerelateerde leverfibrose en ontstekingsremming bij obesitas, diabetes mellitus en metabool syndroom.(27-32) Activering van PPAR- is therapeutisch aangrijpingspunt bij cystische fibrose en systemische sclerose.( 33,34) 3