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Transcription-replication conflict orientation modulates R-loop levels and activates distinct DNA damage responses

Their destructive effects may contribute to the diseases initiation and propagation, as they damage the gut lining and activate inflammatory signaling pathways, further exacerbating the inflammation

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There is a substantial increase in the total quantity of bacteria and notable changes in the composition of the gastrointestinal microbiota during pregnancy, especially in the latter stages

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