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Ellwood-Yen K, Wang F, Travins J, Chen Y, Yang H, Straley K et al

It has shown efficacy in animal models of inflammatory bowel disease (IBD), gastric ulcers, and "leaky gut." Systemic anti-inflammatory effects: It appears to dampen inflammatory cascades without the immune-suppressing risks associated with corticosteroids

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S., Juglanin Ameliorates LPSinduced Neuroinflammation in Animal Models of Parkinson's Disease and Cell Culture via Inactivating TLR4/NFB Pathway, Biomedicine & Pharmacotherapy 97 (2018): 10111019

Redness or rashes: These usually only happen where the product was used

156,157,158 Zhang et al