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When neurological symptoms are present, more intensive treatment is required: 1 mg hydroxocobalamin on alternate days until no further improvement occurs, followed by maintenance therapy every two months

A dose-dependent decrease in body weight was shown, ranging from -1.3 kg in the placebo group to -1.4 kg in the 0.03 mg/kg leptin-treated group, and to -7.1 kg in the 0.30 mg/kg leptin-treated group (8)

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All evidence is from animal models, with no published human data

As an injectable vitamin B12 solution, it bypasses the digestive system and allows direct absorption, making it suitable for individuals with low or deficient vitamin B12 levels