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Enzymatic reactions involving ROS production include prostaglandin synthesis, respiratory chain, phagocytosis, and cytochrome P450 system, etc

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Quercetin ameliorates cognitive impairment in depression by targeting HSP90 to inhibit NLRP3 inflammasome activation

In this context, orally administered compounds such as polyphenols, flavonoids, and carotenoids initially undergo first-pass hepatic metabolism

Moreover, mitochondrial quality control ensures proper mitochondrial function by removing damaged or unneeded mitochondrial proteins or, at some point, the entire organism (Song et al., 2021)

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