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Nat Genet 39(2):207 Rioux JD, Xavier RJ, Taylor KD, Silverberg MS, Goyette P, Huett A et al (2007) Genome-wide association study identifies new susceptibility loci for Crohn disease and implicates autophagy in disease pathogenesis

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In mice, deletion of GPX4 triggers ferroptosis and inhibits the production of IgM antibodies in response to Streptococcus pneumoniae

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CD44 variant regulates redox status in cancer cells by stabilizing the xCT subunit of system xc(-) and thereby promotes tumor growth