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A key limitation of this study is that while quercetins bioavailability and tissue distribution have been previously reported, we did not directly measure its concentrations in the liver or ovary

provided evidence that the interplay between the signals of mechanistic target of rapamycin kinase (mTOR) and GPX4 modulates autophagydependent ferroptosis in human pancreatic cancer cells, and the downregulated expression of GPX4 enhances the anti-cancer activity of rapamycin in vitro or in vivo by promoting ferroptosis and suppressing autophagy [38]

The integrative human microbiome project

An herbal galactagogue mixture increases milk production and aquaporin protein expression in the mammary glands of lactating rats

Some researchers claim that deficiencies, especially in vitamin D, magnesium, zinc, and B vitamins, directly hinder insulin receptor signaling and ovarian hormone production, contributing to PCOS development

This downregulation subsequently inhibits NLRP3 inflammasome activation, leading to upregulation of GPX4/SLC7A11 or downregulation of ACSL4/ALOX15, and ultimately suppressing both ferroptosis and neuroinflammation